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"Graphene-based nanomaterials are being paired with common over-the-counter drugs like ibuprofen. "Innovations" like these are becoming increasingly important in the era of biodigital convergence, where medicine, advanced materials, and digital technologies are rapidly merging the physical and digital world..
This paper states that graphene oxide and its modified forms are being explored as smart drug-delivery carriers for ibuprofen because their ultra-thin, high-surface-area sheets can hold large amounts of the drug and release it in a controlled way inside the body. Their surfaces contain oxygen-based chemical groups that make them water-dispersible and allow ibuprofen to attach either between the layers or along the sheet edges through hydrophobic and π–π interactions. According to the authors this lets graphene oxide protect ibuprofen as it passes through the harsh, acidic environment of the stomach—where the drug normally causes irritation—and then release much more of it later in the intestine, where absorption happens. By tuning the surface chemistry of graphene (such as adding sulfonic or carboxyl groups), researchers can control how tightly ibuprofen binds and how quickly it is released, making graphene-based nanomaterials promising candidates for "safer," more efficient ibuprofen delivery.
Provided below is a section-by-section overview of the paper "Comparative Study of Various Graphene Oxide Structures as Efficient Drug Release Systems for Ibuprofen""
https://www.mdpi.com/2673-9623/2/2/6!!!!!
"Graphene-based nanomaterials are being paired with common over-the-counter drugs like ibuprofen. "Innovations" like these are becoming increasingly important in the era of biodigital convergence, where medicine, advanced materials, and digital technologies are rapidly merging the physical and digital world.. 👇
This paper states that graphene oxide and its modified forms are being explored as smart drug-delivery carriers for ibuprofen because their ultra-thin, high-surface-area sheets can hold large amounts of the drug and release it in a controlled way inside the body. Their surfaces contain oxygen-based chemical groups that make them water-dispersible and allow ibuprofen to attach either between the layers or along the sheet edges through hydrophobic and π–π interactions. According to the authors this lets graphene oxide protect ibuprofen as it passes through the harsh, acidic environment of the stomach—where the drug normally causes irritation—and then release much more of it later in the intestine, where absorption happens. By tuning the surface chemistry of graphene (such as adding sulfonic or carboxyl groups), researchers can control how tightly ibuprofen binds and how quickly it is released, making graphene-based nanomaterials promising candidates for "safer," more efficient ibuprofen delivery.
Provided below is a section-by-section overview of the paper "Comparative Study of Various Graphene Oxide Structures as Efficient Drug Release Systems for Ibuprofen""
https://www.mdpi.com/2673-9623/2/2/6
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